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Access to 6-hydroxy indolizines and related imidazo[1,5-a]pyridines through the S(N)2 substitution/condensation/tautomerization cascade process

A simple and efficient cascade reaction was developed for the construction of hydroxy substituted indolizines from pyrrole-2-carbaldehydes and commercially available 4-halogenated acetoacetic esters. Their optical properties were also evaluated.

Detalles Bibliográficos
Autores principales: Duan, Guiyun, Liu, Hao, Zhang, Liqing, Yuan, Chunhao, Li, Yongchao, Ge, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036982/
https://www.ncbi.nlm.nih.gov/pubmed/35478892
http://dx.doi.org/10.1039/d1ra04425g

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