Cargando…

Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats

Agathisflavone is a flavonoid with anti-neuroinflammatory and myelinogenic properties, being also capable to induce neurogenesis. This study evaluated the therapeutic effects of agathisflavone—both as a pharmacological therapy administered in vivo and as an in vitro pre-treatment aiming to enhance r...

Descripción completa

Detalles Bibliográficos
Autores principales:	do Nascimento, Ravena P., de Jesus, Lívia B., Oliveira-Junior, Markley S., Almeida, Aurea M., Moreira, Eduardo L. T., Paredes, Bruno D., David, Jorge M., Souza, Bruno S. F., de Fátima D. Costa, Maria, Butt, Arthur M., Silva, Victor Diogenes A., Costa, Silvia L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037239/ https://www.ncbi.nlm.nih.gov/pubmed/35479309 http://dx.doi.org/10.3389/fphar.2022.858190

Ejemplares similares

The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination
por: de Almeida, Monique Marylin Alves, et al.
Publicado: (2020)

Phytoestrogen Agathisflavone Ameliorates Neuroinflammation-Induced by LPS and IL-1β and Protects Neurons in Cocultures of Glia/Neurons
por: de Almeida, Monique Marylin Alves, et al.
Publicado: (2020)

In vitro antioxidant properties of the biflavonoid agathisflavone
por: Andrade, Anderson Wilbur Lopes, et al.
Publicado: (2018)

The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome
por: dos Santos, Balbino Lino, et al.
Publicado: (2023)

The Role of Astrocytes in Metabolism and Neurotoxicity of the Pyrrolizidine Alkaloid Monocrotaline, the Main Toxin of Crotalaria retusa
por: Pitanga, Bruno Penas Seara, et al.
Publicado: (2012)

Agathisflavone, a natural biflavonoid that inhibits SARS-CoV-2 replication by targeting its proteases
por: Chaves, Otávio Augusto, et al.
Publicado: (2022)

Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma
por: do Nascimento, Ravena Pereira, et al.
Publicado: (2022)

Radiographic assessment of hips in patients with spinal cord injury
por: Grynwald, Jean, et al.
Publicado: (2012)

Case Report: Galvanic Vestibular Stimulation in the Chronic Spinal Cord Injury Patient
por: Nascimento, Tais Nunes, et al.
Publicado: (2022)

Case report – Gluteal hematoma in two spinal cord patients on enoxaparin for venous thromboembolism prophylaxis: evidence needed for a wiser choice
por: de Almeida, Rodrigo Lanna, et al.
Publicado: (2019)

Functional result relating to the positioning of the graft in anterior cruciate ligament reconstruction()
por: de Melo Silva Júnior, Otávio, et al.
Publicado: (2015)

Human-umbilical cord matrix mesenchymal cells improved left ventricular contractility independently of infarct size in swine myocardial infarction with reperfusion
por: Raposo, Luís, et al.
Publicado: (2023)

TMD and chronic pain: A current view
por: Furquim, Bruno D'Aurea, et al.
Publicado: (2015)

Static and Dynamic Strength Indicators in Paralympic Power-Lifters with and without Spinal Cord Injury
por: Teles, Luan José Lopes, et al.
Publicado: (2021)

Intramedullary spinal cord lesions in an immunocompromised host due to Mycobacterium haemophilum
por: Kon, Shelley, et al.
Publicado: (2019)

Spinal cord and cutaneous involvement in paracoccidioidomycosis
por: França, Andrea Fernandes Eloy da Costa, et al.
Publicado: (2021)

Spinal Cord Injury and Loss of Cortical Inhibition
por: Benedetti, Bruno, et al.
Publicado: (2022)

Neuroimmunomodulatory and Neuroprotective Effects of the Flavonoid Apigenin in in vitro Models of Neuroinflammation Associated With Alzheimer’s Disease
por: Dourado, Naiara Silva, et al.
Publicado: (2020)

Unsuspected Involvement of Spinal Cord in Alzheimer Disease
por: Lorenzi, Roberta Maria, et al.
Publicado: (2020)

Tailoring PLA/ABS Blends Compatibilized with SEBS-g-MA through Annealing Heat Treatment
por: Costa, Anna Raffaela de Matos, et al.
Publicado: (2023)

Hospitalization, mortality and public healthcare expenditure in Brazil during the COVID-19 crisis: vulnerabilities in the spotlight
por: do Nascimento, Israel Júnior Borges, et al.
Publicado: (2021)

Exercise alleviates hypoalgesia and increases the level of calcitonin gene-related peptide in the dorsal horn of the spinal cord of diabetic rats
por: do Nascimento, Patrícia Severo, et al.
Publicado: (2012)

Spinal cord compression by a pulmonary hernia()
por: Baldo, Guilherme Valdir, et al.
Publicado: (2018)

Astrocyte reactivity in spinal cord and functional impairment after tendon injury in rats
por: Mendes, Áurea Gabriela Rodrigues, et al.
Publicado: (2021)

Diaphragmatic pacing stimulation in spinal cord injury: anesthetic and perioperative management
por: Tedde, Miguel L., et al.
Publicado: (2012)

CLINICAL AND RADIOGRAPHIC EVALUATION OF ELBOWS FROM SPINAL CORD INJURIED PATIENTS
por: Casimiro, Fabiana de Godoy, et al.
Publicado: (2016)

Clinical Trials Using Mesenchymal Stem Cells for Spinal Cord Injury: Challenges in Generating Evidence
por: de Araújo, Lila Teixeira, et al.
Publicado: (2022)

Drug Repurposing for Paracoccidioidomycosis Through a Computational Chemogenomics Framework
por: de Oliveira, Amanda Alves, et al.
Publicado: (2019)

Minimally invasive intrathecal spinal cord imaging with optical coherence tomography
por: Pasarikovski, Christopher R., et al.
Publicado: (2021)

Spinal cord herniation after brachial plexus injury
por: Bamps, Sven, et al.
Publicado: (2017)

Development and repair of blood vessels in the zebrafish spinal cord
por: Ribeiro, Ana, et al.
Publicado: (2023)

Crop-Livestock Integration Improves Physical Soil, Agronomic and Environmental Aspects in Soybean Cultivation
por: Lima, Jordaanny Danyelly Pereira, et al.
Publicado: (2023)

A rare cause of thoracic cord compression
por: Teixeira, Anderson Alexsander Rodrigues, et al.
Publicado: (2018)

Calculation of the Minimal Important Clinical Difference of the Lysholm and IKDC Scores After Anterior Cruciate Ligament Reconstruction
por: Nascimento, Bruno Fajardo do, et al.
Publicado: (2022)

Transient Spinal Cord Ischemia as Presenting Manifestation of Polycythemia Vera
por: Costa, Sónia, et al.
Publicado: (2011)

Innovative treatment using tilapia skin as a xenograft for partial thickness burns after a gunpowder explosion
por: Lima-Junior, Edmar Maciel, et al.
Publicado: (2019)

Translating promising strategies for bowel and bladder management in spinal cord injury
por: Wheeler, Tracey L., et al.
Publicado: (2018)

Labor Market Integration of People with Disabilities: Results from the Swiss Spinal Cord Injury Cohort Study
por: Reinhardt, Jan D., et al.
Publicado: (2016)

Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration
por: Cura Costa, Emanuel, et al.
Publicado: (2021)

Environmental cues determine the fate of astrocytes after spinal cord injury
por: Nathan, Fatima M., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3r1jc4tih77mk38pqf6hfgacur