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A mathematical model to quantify RYR Ca(2+) leak and associated heat production in resting human skeletal muscle fibers
Cycling of Ca(2+) between the sarcoplasmic reticulum (SR) and myoplasm is an important component of skeletal muscle resting metabolism. As part of this cycle, Ca(2+) leaks from the SR into the myoplasm and is pumped back into the SR using ATP, which leads to the consumption of O(2) and generation of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Rockefeller University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037342/ https://www.ncbi.nlm.nih.gov/pubmed/35311921 http://dx.doi.org/10.1085/jgp.202112994 |