Calcium current modulation by the γ(1) subunit depends on alternative splicing of Ca(V)1.1

The skeletal muscle voltage-gated calcium channel (Ca(V)1.1) primarily functions as a voltage sensor for excitation–contraction coupling. Conversely, its ion-conducting function is modulated by multiple mechanisms within the pore-forming α(1S) subunit and the auxiliary α(2)δ-1 and γ(1) subunits. In...

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Detalles Bibliográficos
Autores principales: El Ghaleb, Yousra, Ortner, Nadine J., Posch, Wilfried, Fernández-Quintero, Monica L., Tuinte, Wietske E., Monteleone, Stefania, Draheim, Henning J., Liedl, Klaus R., Wilflingseder, Doris, Striessnig, Jörg, Tuluc, Petronel, Flucher, Bernhard E., Campiglio, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037348/
https://www.ncbi.nlm.nih.gov/pubmed/35349630
http://dx.doi.org/10.1085/jgp.202113028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037348/
https://www.ncbi.nlm.nih.gov/pubmed/35349630
http://dx.doi.org/10.1085/jgp.202113028

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