CAMK2/CaMKII activates MLKL in short-term starvation to facilitate autophagic flux

MLKL (mixed lineage kinase domain like pseudokinase) is a well-known core component of necrosome that executes necroptotic cell death upon phosphorylation by RIPK3 (receptor interacting serine/threonine kinase 3). Recent studies also implicate a role of MLKL in endosomal trafficking, which is not al...

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Detalles Bibliográficos
Autores principales: Zhan, Qionghui, Jeon, Jaepyo, Li, Ying, Huang, Yu, Xiong, Jian, Wang, Qiaochu, Xu, Tian-Le, Li, Yong, Ji, Fu-Hai, Du, Guangwei, Zhu, Michael X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037428/
https://www.ncbi.nlm.nih.gov/pubmed/34282994
http://dx.doi.org/10.1080/15548627.2021.1954348

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