Cargando…
Real-time luminescence enables continuous drug–response analysis in adherent and suspension cell lines
The drug-induced proliferation (DIP) rate is a metric of in vitro drug response that avoids inherent biases in commonly used metrics such as 72 h viability. However, DIP rate measurements rely on direct cell counting over time, a laborious task that is subject to numerous challenges, including the n...
Autores principales: | Wandishin, Clayton M., Robbins, Charles John, Tyson, Darren R., Harris, Leonard A., Quaranta, Vito |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037430/ https://www.ncbi.nlm.nih.gov/pubmed/35443861 http://dx.doi.org/10.1080/15384047.2022.2065182 |
Ejemplares similares
-
An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability
por: Hayford, Corey E., et al.
Publicado: (2021) -
A drift-diffusion checkpoint model predicts a highly variable and growth-factor-sensitive portion of the cell cycle G1 phase
por: Jones, Zack W., et al.
Publicado: (2018) -
Thunor: visualization and analysis of high-throughput dose–response datasets
por: Lubbock, Alexander L R, et al.
Publicado: (2021) -
Involvement of Epithelial–Mesenchymal Transition Genes in Small Cell Lung Cancer Phenotypic Plasticity
por: Groves, Sarah M., et al.
Publicado: (2023) -
An unbiased metric of antiproliferative drug effect in vitro
por: Harris, Leonard A., et al.
Publicado: (2016)