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Development of QSAR models for in silico screening of antibody solubility

Although monoclonal antibodies (mAbs) have been shown to be extremely effective in treating a number of diseases, they often suffer from poor developability attributes, such as high viscosity and low solubility at elevated concentrations. Since experimental candidate screening is often materials and...

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Detalles Bibliográficos
Autores principales:	Han, Xuan, Shih, James, Lin, Yuhao, Chai, Qing, Cramer, Steven M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037471/ https://www.ncbi.nlm.nih.gov/pubmed/35442164 http://dx.doi.org/10.1080/19420862.2022.2062807

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