Persulfidation is the mechanism underlying sulfide-signaling of autophagy

In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H(2)S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups...

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Autores principales: Gotor, Cecilia, Aroca, Angeles, Romero, Luis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Commentary and Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037506/
https://www.ncbi.nlm.nih.gov/pubmed/34097571
http://dx.doi.org/10.1080/15548627.2021.1936357
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author Gotor, Cecilia
Aroca, Angeles
Romero, Luis C.
author_facet Gotor, Cecilia
Aroca, Angeles
Romero, Luis C.
author_sort Gotor, Cecilia
collection PubMed
description In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H(2)S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism.
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spelling pubmed-90375062022-04-26 Persulfidation is the mechanism underlying sulfide-signaling of autophagy Gotor, Cecilia Aroca, Angeles Romero, Luis C. Autophagy Commentary and Views In this commentary, we highlight the findings described in a recent paper regarding the mechanism of H(2)S regulation of macroautophagy/autophagy in mammalian cells and discuss the similarities/divergencies with plant cells. The main outcome is that the posttranslational modification of thiol groups of cysteine residues to form persulfides is a conserved molecular mechanism. Taylor & Francis 2021-06-07 /pmc/articles/PMC9037506/ /pubmed/34097571 http://dx.doi.org/10.1080/15548627.2021.1936357 Text en © 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Commentary and Views
Gotor, Cecilia
Aroca, Angeles
Romero, Luis C.
Persulfidation is the mechanism underlying sulfide-signaling of autophagy
title Persulfidation is the mechanism underlying sulfide-signaling of autophagy
title_full Persulfidation is the mechanism underlying sulfide-signaling of autophagy
title_fullStr Persulfidation is the mechanism underlying sulfide-signaling of autophagy
title_full_unstemmed Persulfidation is the mechanism underlying sulfide-signaling of autophagy
title_short Persulfidation is the mechanism underlying sulfide-signaling of autophagy
title_sort persulfidation is the mechanism underlying sulfide-signaling of autophagy
topic Commentary and Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037506/
https://www.ncbi.nlm.nih.gov/pubmed/34097571
http://dx.doi.org/10.1080/15548627.2021.1936357
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