Piperine promotes autophagy flux by P2RX4 activation in SNCA/α-synuclein-induced Parkinson disease model

Olfactory dysfunction, one of the earliest non-motor symptoms of Parkinson disease (PD), is accompanied by abnormal deposition of SNCA/α-synuclein in the olfactory bulb (OB). The macroautophagy/autophagy-lysosome pathway (ALP) plays an important role in degrading pathological SNCA and modulating thi...

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Detalles Bibliográficos
Autores principales: Li, Ruolin, Lu, Yongquan, Zhang, Qidi, Liu, Weijin, Yang, Runing, Jiao, Jie, Liu, Jia, Gao, Ge, Yang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037522/
https://www.ncbi.nlm.nih.gov/pubmed/34092198
http://dx.doi.org/10.1080/15548627.2021.1937897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037522/
https://www.ncbi.nlm.nih.gov/pubmed/34092198
http://dx.doi.org/10.1080/15548627.2021.1937897

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