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Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection

In this paper, we design opto-plasmonic sensors by the engineered arrangement of gold-nanospheres. We use DNA-gold nanoparticle (GNP) core–shells and DNA rods as junctions between GNPs with a fishnet ground layer for controlling and improving the absorbance and reflection in the range of 100–300 THz...

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Autores principales: Osanloo, Nahid, Ahmadi, Vahid, Naser-Moghaddasi, Mohammad, Darabi, Elham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037639/
https://www.ncbi.nlm.nih.gov/pubmed/35480674
http://dx.doi.org/10.1039/d1ra03079e
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author Osanloo, Nahid
Ahmadi, Vahid
Naser-Moghaddasi, Mohammad
Darabi, Elham
author_facet Osanloo, Nahid
Ahmadi, Vahid
Naser-Moghaddasi, Mohammad
Darabi, Elham
author_sort Osanloo, Nahid
collection PubMed
description In this paper, we design opto-plasmonic sensors by the engineered arrangement of gold-nanospheres. We use DNA-gold nanoparticle (GNP) core–shells and DNA rods as junctions between GNPs with a fishnet ground layer for controlling and improving the absorbance and reflection in the range of 100–300 THz. Based on available data, we check the effects of healthy and cancerous cells on the reflection parameter. Here, we demonstrate how the DNA junctions and distance between the nanospheres can be considered to modify the reflection. These structures can be utilized as opto-plasmonic sensors with high sensitivity to distinguish materials in terms of refractive indices. We can use an array of these sensors for both spectroscopy and optical imaging on a real scale. The proposed structures with different topologies are analyzed and their figure of merits (FOM) and sensitivities are obtained. The structure based on the DNA rods as junctions between GNPs shows the best FOM value of 340 RIU(−1) and the core–shell heptamer structure has the best sensitivity of about 1287 nm RIU(−1).
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spelling pubmed-90376392022-04-26 Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection Osanloo, Nahid Ahmadi, Vahid Naser-Moghaddasi, Mohammad Darabi, Elham RSC Adv Chemistry In this paper, we design opto-plasmonic sensors by the engineered arrangement of gold-nanospheres. We use DNA-gold nanoparticle (GNP) core–shells and DNA rods as junctions between GNPs with a fishnet ground layer for controlling and improving the absorbance and reflection in the range of 100–300 THz. Based on available data, we check the effects of healthy and cancerous cells on the reflection parameter. Here, we demonstrate how the DNA junctions and distance between the nanospheres can be considered to modify the reflection. These structures can be utilized as opto-plasmonic sensors with high sensitivity to distinguish materials in terms of refractive indices. We can use an array of these sensors for both spectroscopy and optical imaging on a real scale. The proposed structures with different topologies are analyzed and their figure of merits (FOM) and sensitivities are obtained. The structure based on the DNA rods as junctions between GNPs shows the best FOM value of 340 RIU(−1) and the core–shell heptamer structure has the best sensitivity of about 1287 nm RIU(−1). The Royal Society of Chemistry 2021-08-09 /pmc/articles/PMC9037639/ /pubmed/35480674 http://dx.doi.org/10.1039/d1ra03079e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Osanloo, Nahid
Ahmadi, Vahid
Naser-Moghaddasi, Mohammad
Darabi, Elham
Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection
title Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection
title_full Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection
title_fullStr Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection
title_full_unstemmed Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection
title_short Engineered nano-sphere array of gold-DNA core–shells and junctions as opto-plasmonic sensors for biodetection
title_sort engineered nano-sphere array of gold-dna core–shells and junctions as opto-plasmonic sensors for biodetection
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037639/
https://www.ncbi.nlm.nih.gov/pubmed/35480674
http://dx.doi.org/10.1039/d1ra03079e
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