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Facile synthesis and biological evaluation of tryptamine-piperazine-2,5-dione conjugates as anticancer agents

A facile and efficient route to synthesize N-heterocyclic fused tryptamine-piperazine-2,5-dione conjugates was developed via a post-Ugi cascade reaction. The targeted compounds were prepared by means of a mild reaction and simple operation procedure, which could be applied to a broad scope of starti...

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Detalles Bibliográficos
Autores principales: Meng, Jiang-Ping, Li, Shi-Qiang, Tang, Yan, Xu, Zhi-Gang, Chen, Zhong-Zhu, Gao, Li-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037805/
https://www.ncbi.nlm.nih.gov/pubmed/35480764
http://dx.doi.org/10.1039/d1ra03740d