Targeting CXCL12/CXCR4 Signaling with AMD3100 Might Selectively Suppress CXCR4+ T-Cell Chemotaxis Leading to the Alleviation of Chronic Prostatitis

BACKGROUND: Chronic nonbacterial prostatitis (CNP) has a high incidence, low cure rate, and unclear pathogenesis. Here, we aimed to systematically identify effective diagnostic and therapeutic targets for CNP. METHODS: Prostate tissues were obtained from established mouse models and negative control...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Liu, Yi, Chen, Jing, Chen, Lei, Zhang, Li, Chen, Xianguo, Hao, Zongyao, Liang, Chaozhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037856/
https://www.ncbi.nlm.nih.gov/pubmed/35479835
http://dx.doi.org/10.2147/JIR.S352336

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