Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography

We present a case of Anti-IgLON 5 encephalitis with Lewy body dementia. (18)F fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan and 99 mTc-TRODAT-1 SPECT/CT scan were done. 99 mTc-TRODAT-1 scan findings revealed severely reduced concentration of dopamine trans...

Descripción completa

Detalles Bibliográficos
Autores principales: Seniaray, Nikhil, Verma, Ritu, Ranjan, Rajeev, Belho, Ethel, Mahajan, Harsh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037863/
https://www.ncbi.nlm.nih.gov/pubmed/35478670
http://dx.doi.org/10.4103/ijnm.ijnm_108_21
_version_ 1784693809020403712
author Seniaray, Nikhil
Verma, Ritu
Ranjan, Rajeev
Belho, Ethel
Mahajan, Harsh
author_facet Seniaray, Nikhil
Verma, Ritu
Ranjan, Rajeev
Belho, Ethel
Mahajan, Harsh
author_sort Seniaray, Nikhil
collection PubMed
description We present a case of Anti-IgLON 5 encephalitis with Lewy body dementia. (18)F fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan and 99 mTc-TRODAT-1 SPECT/CT scan were done. 99 mTc-TRODAT-1 scan findings revealed severely reduced concentration of dopamine transporter in bilateral basal ganglia, suggestive of a degenerative parkinsonian disorder. 18F-FDG PET scan findings were suggestive of moderate-to-severe hypometabolism in the bilateral parieto-temporal and bilateral occipital cortices including the primary visual cortices, supporting Lewy body spectrum disease with associated hypermetabolism in the bilateral sensorimotor cortices, bilateral basal ganglia, thalami, brain stem, and bilateral cerebellar hemispheres suggestive of inflammatory pathology.
format Online
Article
Text
id pubmed-9037863
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-90378632022-04-26 Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography Seniaray, Nikhil Verma, Ritu Ranjan, Rajeev Belho, Ethel Mahajan, Harsh Indian J Nucl Med Interesting Image We present a case of Anti-IgLON 5 encephalitis with Lewy body dementia. (18)F fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scan and 99 mTc-TRODAT-1 SPECT/CT scan were done. 99 mTc-TRODAT-1 scan findings revealed severely reduced concentration of dopamine transporter in bilateral basal ganglia, suggestive of a degenerative parkinsonian disorder. 18F-FDG PET scan findings were suggestive of moderate-to-severe hypometabolism in the bilateral parieto-temporal and bilateral occipital cortices including the primary visual cortices, supporting Lewy body spectrum disease with associated hypermetabolism in the bilateral sensorimotor cortices, bilateral basal ganglia, thalami, brain stem, and bilateral cerebellar hemispheres suggestive of inflammatory pathology. Wolters Kluwer - Medknow 2022 2022-03-25 /pmc/articles/PMC9037863/ /pubmed/35478670 http://dx.doi.org/10.4103/ijnm.ijnm_108_21 Text en Copyright: © 2022 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Interesting Image
Seniaray, Nikhil
Verma, Ritu
Ranjan, Rajeev
Belho, Ethel
Mahajan, Harsh
Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography
title Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography
title_full Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography
title_fullStr Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography
title_full_unstemmed Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography
title_short Lewy Body Dementia Associated with Anti-IgLON 5 Encephalitis Detected on (18)F Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography and 99mTc-TRODAT Single-Photon Emission Computed Tomography/Computed Tomography
title_sort lewy body dementia associated with anti-iglon 5 encephalitis detected on (18)f fluorodeoxyglucose positron emission tomography/computed tomography and 99mtc-trodat single-photon emission computed tomography/computed tomography
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037863/
https://www.ncbi.nlm.nih.gov/pubmed/35478670
http://dx.doi.org/10.4103/ijnm.ijnm_108_21
work_keys_str_mv AT seniaraynikhil lewybodydementiaassociatedwithantiiglon5encephalitisdetectedon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyand99mtctrodatsinglephotonemissioncomputedtomographycomputedtomography
AT vermaritu lewybodydementiaassociatedwithantiiglon5encephalitisdetectedon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyand99mtctrodatsinglephotonemissioncomputedtomographycomputedtomography
AT ranjanrajeev lewybodydementiaassociatedwithantiiglon5encephalitisdetectedon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyand99mtctrodatsinglephotonemissioncomputedtomographycomputedtomography
AT belhoethel lewybodydementiaassociatedwithantiiglon5encephalitisdetectedon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyand99mtctrodatsinglephotonemissioncomputedtomographycomputedtomography
AT mahajanharsh lewybodydementiaassociatedwithantiiglon5encephalitisdetectedon18ffluorodeoxyglucosepositronemissiontomographycomputedtomographyand99mtctrodatsinglephotonemissioncomputedtomographycomputedtomography

Ejemplares similares