Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis

Calcinosis of soft tissue is a rare but known complication of dermatomyositis (DM), mostly associated with juvenile DM and rare in adult DM. Bone scan with Tc-99m Methylene diphosphonate is useful in disease mapping and has high sensitivity to know the extent of calcinosis. However, there is scanty...

Descripción completa

Detalles Bibliográficos
Autores principales: Patro, P. Sai Sradha, Patra, Subhabrata, Kumar, Rajesh, Agrawal, Kanhaiyalal, Parida, Girish Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037864/
https://www.ncbi.nlm.nih.gov/pubmed/35478689
http://dx.doi.org/10.4103/ijnm.ijnm_106_21
_version_ 1784693809272061952
author Patro, P. Sai Sradha
Patra, Subhabrata
Kumar, Rajesh
Agrawal, Kanhaiyalal
Parida, Girish Kumar
author_facet Patro, P. Sai Sradha
Patra, Subhabrata
Kumar, Rajesh
Agrawal, Kanhaiyalal
Parida, Girish Kumar
author_sort Patro, P. Sai Sradha
collection PubMed
description Calcinosis of soft tissue is a rare but known complication of dermatomyositis (DM), mostly associated with juvenile DM and rare in adult DM. Bone scan with Tc-99m Methylene diphosphonate is useful in disease mapping and has high sensitivity to know the extent of calcinosis. However, there is scanty literature available on the utility of bone scan in treatment response evaluation in DM. Rituximab has been found useful in adult DM with calcinosis unresponsive to conventional treatment. We describe an interesting case showing partial response to rituximab on bone scan with single-photon emission tomography-computed tomography.
format Online
Article
Text
id pubmed-9037864
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-90378642022-04-26 Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis Patro, P. Sai Sradha Patra, Subhabrata Kumar, Rajesh Agrawal, Kanhaiyalal Parida, Girish Kumar Indian J Nucl Med Case Report Calcinosis of soft tissue is a rare but known complication of dermatomyositis (DM), mostly associated with juvenile DM and rare in adult DM. Bone scan with Tc-99m Methylene diphosphonate is useful in disease mapping and has high sensitivity to know the extent of calcinosis. However, there is scanty literature available on the utility of bone scan in treatment response evaluation in DM. Rituximab has been found useful in adult DM with calcinosis unresponsive to conventional treatment. We describe an interesting case showing partial response to rituximab on bone scan with single-photon emission tomography-computed tomography. Wolters Kluwer - Medknow 2022 2022-03-25 /pmc/articles/PMC9037864/ /pubmed/35478689 http://dx.doi.org/10.4103/ijnm.ijnm_106_21 Text en Copyright: © 2022 Indian Journal of Nuclear Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Patro, P. Sai Sradha
Patra, Subhabrata
Kumar, Rajesh
Agrawal, Kanhaiyalal
Parida, Girish Kumar
Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis
title Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis
title_full Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis
title_fullStr Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis
title_full_unstemmed Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis
title_short Assessment of Treatment Response by Bone SPECT-CT in a Case of Dermatomyositis with Calcinosis Cutis
title_sort assessment of treatment response by bone spect-ct in a case of dermatomyositis with calcinosis cutis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037864/
https://www.ncbi.nlm.nih.gov/pubmed/35478689
http://dx.doi.org/10.4103/ijnm.ijnm_106_21
work_keys_str_mv AT patropsaisradha assessmentoftreatmentresponsebybonespectctinacaseofdermatomyositiswithcalcinosiscutis
AT patrasubhabrata assessmentoftreatmentresponsebybonespectctinacaseofdermatomyositiswithcalcinosiscutis
AT kumarrajesh assessmentoftreatmentresponsebybonespectctinacaseofdermatomyositiswithcalcinosiscutis
AT agrawalkanhaiyalal assessmentoftreatmentresponsebybonespectctinacaseofdermatomyositiswithcalcinosiscutis
AT paridagirishkumar assessmentoftreatmentresponsebybonespectctinacaseofdermatomyositiswithcalcinosiscutis

Ejemplares similares