Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19

Myoclonus and ataxia, with or without opsoclonus, have recently been recognized as a central nervous system syndrome associated with coronavirus disease-2019 (COVID-19). A 52-year-old Japanese man developed myoclonus and ataxia 16 days after the onset of COVID-19. Brain single-photon emission comput...

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Autores principales: Osawa, Kenta, Sugiyama, Atsuhiko, Uzawa, Akiyuki, Hirano, Shigeki, Yamamoto, Tatsuya, Nezu, Masahiko, Araki, Nobuyuki, Kano, Hiroki, Kuwabara, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038453/
https://www.ncbi.nlm.nih.gov/pubmed/35110499
http://dx.doi.org/10.2169/internalmedicine.9171-21
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author Osawa, Kenta
Sugiyama, Atsuhiko
Uzawa, Akiyuki
Hirano, Shigeki
Yamamoto, Tatsuya
Nezu, Masahiko
Araki, Nobuyuki
Kano, Hiroki
Kuwabara, Satoshi
author_facet Osawa, Kenta
Sugiyama, Atsuhiko
Uzawa, Akiyuki
Hirano, Shigeki
Yamamoto, Tatsuya
Nezu, Masahiko
Araki, Nobuyuki
Kano, Hiroki
Kuwabara, Satoshi
author_sort Osawa, Kenta
collection PubMed
description Myoclonus and ataxia, with or without opsoclonus, have recently been recognized as a central nervous system syndrome associated with coronavirus disease-2019 (COVID-19). A 52-year-old Japanese man developed myoclonus and ataxia 16 days after the onset of COVID-19. Brain single-photon emission computed tomography (SPECT) revealed hyperperfusion in the cerebellum and hypoperfusion in the cerebral cortices with frontal predominance during the acute stage, which improved over two months. This study indicates that brain perfusion SPECT can be effective in detecting functional alterations in COVID-19-related myoclonus and ataxia.
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spelling pubmed-90384532022-05-06 Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19 Osawa, Kenta Sugiyama, Atsuhiko Uzawa, Akiyuki Hirano, Shigeki Yamamoto, Tatsuya Nezu, Masahiko Araki, Nobuyuki Kano, Hiroki Kuwabara, Satoshi Intern Med Case Report Myoclonus and ataxia, with or without opsoclonus, have recently been recognized as a central nervous system syndrome associated with coronavirus disease-2019 (COVID-19). A 52-year-old Japanese man developed myoclonus and ataxia 16 days after the onset of COVID-19. Brain single-photon emission computed tomography (SPECT) revealed hyperperfusion in the cerebellum and hypoperfusion in the cerebral cortices with frontal predominance during the acute stage, which improved over two months. This study indicates that brain perfusion SPECT can be effective in detecting functional alterations in COVID-19-related myoclonus and ataxia. The Japanese Society of Internal Medicine 2022-02-01 2022-04-01 /pmc/articles/PMC9038453/ /pubmed/35110499 http://dx.doi.org/10.2169/internalmedicine.9171-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Osawa, Kenta
Sugiyama, Atsuhiko
Uzawa, Akiyuki
Hirano, Shigeki
Yamamoto, Tatsuya
Nezu, Masahiko
Araki, Nobuyuki
Kano, Hiroki
Kuwabara, Satoshi
Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19
title Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19
title_full Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19
title_fullStr Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19
title_full_unstemmed Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19
title_short Temporal Changes in Brain Perfusion in a Patient with Myoclonus and Ataxia Syndrome Associated with COVID-19
title_sort temporal changes in brain perfusion in a patient with myoclonus and ataxia syndrome associated with covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038453/
https://www.ncbi.nlm.nih.gov/pubmed/35110499
http://dx.doi.org/10.2169/internalmedicine.9171-21
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