MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a progressive degenerative disorder that leads to joint destruction. Available treatments only target the inflammatory component with minimal impact on joint repair. We recently uncovered a previously unappreciated family of pro-resolving mediators, the mares...

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Detalles Bibliográficos
Autores principales: Pistorius, Kimberly, Ly, Lucy, Souza, Patricia R., Gomez, Esteban A., Koenis, Duco S., Rodriguez, Ana R., Foster, Julie, Sosabowski, Jane, Hopkinson, Mark, Rajeeve, Vinothini, Spur, Bernd W., Pitsillides, Andrew, Pitzalis, Costantino, Dalli, Jesmond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038546/
https://www.ncbi.nlm.nih.gov/pubmed/35430453
http://dx.doi.org/10.1016/j.ebiom.2022.103974

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