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Preparation of DNA interstrand cross-link repair intermediates induced by abasic sites

DNA interstrand cross-links (ICLs) are extremely deleterious DNA lesions, which can block different DNA transactions. A major step in ICL repair involves strand cleavage activities flanking the cross-linking site, also known as unhooking. The cleavage generates a single-stranded DNA remnant attached...

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Detalles Bibliográficos
Autores principales: Tang, Jin, Zhao, Linlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038549/
https://www.ncbi.nlm.nih.gov/pubmed/35492212
http://dx.doi.org/10.1016/j.mex.2022.101687