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Preparation of DNA interstrand cross-link repair intermediates induced by abasic sites
DNA interstrand cross-links (ICLs) are extremely deleterious DNA lesions, which can block different DNA transactions. A major step in ICL repair involves strand cleavage activities flanking the cross-linking site, also known as unhooking. The cleavage generates a single-stranded DNA remnant attached...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038549/ https://www.ncbi.nlm.nih.gov/pubmed/35492212 http://dx.doi.org/10.1016/j.mex.2022.101687 |