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Balancing selection at the human salivary agglutinin gene (DMBT1) driven by host-microbe interactions

Discovering loci under balancing selection in humans can identify loci with alleles that affect response to the environment and disease. Genome variation data have identified the 5′ region of the DMBT1 gene as undergoing balancing selection in humans. DMBT1 encodes the pattern-recognition glycoprote...

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Detalles Bibliográficos
Autores principales: Alharbi, Adel F., Sheng, Nongfei, Nicol, Katie, Strömberg, Nicklas, Hollox, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038570/
https://www.ncbi.nlm.nih.gov/pubmed/35494225
http://dx.doi.org/10.1016/j.isci.2022.104189