Cargando…

Scarless excision of an insertion sequence restores capsule production and virulence in Acinetobacter baumannii

We identify a new mechanism mediating capsule production and virulence in the WHO and CDC priority ESKAPE pathogen Acinetobacter baumannii. Non-capsulated and avirulent bacteria can revert into a capsulated and virulent state upon scarless excision of an ISAba13 insertion sequence under stress condi...

Descripción completa

Detalles Bibliográficos
Autores principales: Whiteway, Clémence, Valcek, Adam, Philippe, Chantal, Strazisar, Mojca, De Pooter, Tim, Mateus, Ivan, Breine, Anke, Van der Henst, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038732/
https://www.ncbi.nlm.nih.gov/pubmed/34949784
http://dx.doi.org/10.1038/s41396-021-01179-3