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Scarless excision of an insertion sequence restores capsule production and virulence in Acinetobacter baumannii

We identify a new mechanism mediating capsule production and virulence in the WHO and CDC priority ESKAPE pathogen Acinetobacter baumannii. Non-capsulated and avirulent bacteria can revert into a capsulated and virulent state upon scarless excision of an ISAba13 insertion sequence under stress condi...

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Detalles Bibliográficos
Autores principales:	Whiteway, Clémence, Valcek, Adam, Philippe, Chantal, Strazisar, Mojca, De Pooter, Tim, Mateus, Ivan, Breine, Anke, Van der Henst, Charles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038732/ https://www.ncbi.nlm.nih.gov/pubmed/34949784 http://dx.doi.org/10.1038/s41396-021-01179-3

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