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Phase retrieval based on deep learning in grating interferometer
Grating interferometry is a promising technique to obtain differential phase contrast images with illumination source of low intrinsic transverse coherence. However, retrieving the phase contrast image from the differential phase contrast image is difficult due to the accumulated noise and artifacts...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038759/ https://www.ncbi.nlm.nih.gov/pubmed/35469034 http://dx.doi.org/10.1038/s41598-022-10551-y |
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author | Oh, Ohsung Kim, Youngju Kim, Daeseung Hussey, Daniel. S. Lee, Seung Wook |
author_facet | Oh, Ohsung Kim, Youngju Kim, Daeseung Hussey, Daniel. S. Lee, Seung Wook |
author_sort | Oh, Ohsung |
collection | PubMed |
description | Grating interferometry is a promising technique to obtain differential phase contrast images with illumination source of low intrinsic transverse coherence. However, retrieving the phase contrast image from the differential phase contrast image is difficult due to the accumulated noise and artifacts from the differential phase contrast image (DPCI) reconstruction. In this paper, we implemented a deep learning-based phase retrieval method to suppress these artifacts. Conventional deep learning based denoising requires noise/clean image pair, but it is not feasible to obtain sufficient number of clean images for grating interferometry. In this paper, we apply a recently developed neural network called Noise2Noise (N2N) that uses noise/noise image pairs for training. We obtained many DPCIs through combination of phase stepping images, and these were used as input/target pairs for N2N training. The application of the N2N network to simulated and measured DPCI showed that the phase contrast images were retrieved with strongly suppressed phase retrieval artifacts. These results can be used in grating interferometer applications which uses phase stepping method. |
format | Online Article Text |
id | pubmed-9038759 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-90387592022-04-27 Phase retrieval based on deep learning in grating interferometer Oh, Ohsung Kim, Youngju Kim, Daeseung Hussey, Daniel. S. Lee, Seung Wook Sci Rep Article Grating interferometry is a promising technique to obtain differential phase contrast images with illumination source of low intrinsic transverse coherence. However, retrieving the phase contrast image from the differential phase contrast image is difficult due to the accumulated noise and artifacts from the differential phase contrast image (DPCI) reconstruction. In this paper, we implemented a deep learning-based phase retrieval method to suppress these artifacts. Conventional deep learning based denoising requires noise/clean image pair, but it is not feasible to obtain sufficient number of clean images for grating interferometry. In this paper, we apply a recently developed neural network called Noise2Noise (N2N) that uses noise/noise image pairs for training. We obtained many DPCIs through combination of phase stepping images, and these were used as input/target pairs for N2N training. The application of the N2N network to simulated and measured DPCI showed that the phase contrast images were retrieved with strongly suppressed phase retrieval artifacts. These results can be used in grating interferometer applications which uses phase stepping method. Nature Publishing Group UK 2022-04-25 /pmc/articles/PMC9038759/ /pubmed/35469034 http://dx.doi.org/10.1038/s41598-022-10551-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Oh, Ohsung Kim, Youngju Kim, Daeseung Hussey, Daniel. S. Lee, Seung Wook Phase retrieval based on deep learning in grating interferometer |
title | Phase retrieval based on deep learning in grating interferometer |
title_full | Phase retrieval based on deep learning in grating interferometer |
title_fullStr | Phase retrieval based on deep learning in grating interferometer |
title_full_unstemmed | Phase retrieval based on deep learning in grating interferometer |
title_short | Phase retrieval based on deep learning in grating interferometer |
title_sort | phase retrieval based on deep learning in grating interferometer |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038759/ https://www.ncbi.nlm.nih.gov/pubmed/35469034 http://dx.doi.org/10.1038/s41598-022-10551-y |
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