Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival

There is ample support for developmental regulation of glioblastoma stem cells. To examine how cell lineage controls glioblastoma stem cell function, we present a cross-species epigenome analysis of mouse and human glioblastoma stem cells. We analyze and compare the chromatin-accessibility landscape...

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Detalles Bibliográficos
Autores principales: Lu, Xi, Maturi, Naga Prathyusha, Jarvius, Malin, Yildirim, Irem, Dang, Yonglong, Zhao, Linxuan, Xie, Yuan, Tan, E-Jean, Xing, Pengwei, Larsson, Rolf, Fryknäs, Mårten, Uhrbom, Lene, Chen, Xingqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038925/
https://www.ncbi.nlm.nih.gov/pubmed/35469026
http://dx.doi.org/10.1038/s41467-022-29912-2

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