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Percentage genome change and chromosome 7q amplification predict sorafenib response in advanced hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) may arise from genomic instability and has dismal outcome. Sorafenib is the first-line treatment for advanced stage HCC, but its therapeutic efficacy is less than 50%. Biomarkers for predicting the therapeutic efficacy of sorafenib administration to patient...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chang Gung University
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038951/ https://www.ncbi.nlm.nih.gov/pubmed/35747997 http://dx.doi.org/10.1016/j.bj.2020.07.001 |