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Percentage genome change and chromosome 7q amplification predict sorafenib response in advanced hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) may arise from genomic instability and has dismal outcome. Sorafenib is the first-line treatment for advanced stage HCC, but its therapeutic efficacy is less than 50%. Biomarkers for predicting the therapeutic efficacy of sorafenib administration to patient...

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Detalles Bibliográficos
Autores principales:	Yu, Ming-Chin, Wu, Tsung-Han, Lee, Chao-Wei, Lee, Yun-Shien, Lian, Jang-Hau, Tsai, Chia-Lung, Hsieh, Sen-Yung, Tsai, Chi-Neu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Chang Gung University 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038951/ https://www.ncbi.nlm.nih.gov/pubmed/35747997 http://dx.doi.org/10.1016/j.bj.2020.07.001

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