Radiolabeled nanomaterials for biomedical applications: radiopharmacy in the era of nanotechnology

BACKGROUND: Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. Nanomedicine, a term for the application of nanotechnology in medical and health fields, uses nanoparticles for several applications such as imaging, diagnostic, targeted cancer thera...

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Detalles Bibliográficos
Autores principales: Pijeira, Martha Sahylí Ortega, Viltres, Herlys, Kozempel, Jan, Sakmár, Michal, Vlk, Martin, İlem-Özdemir, Derya, Ekinci, Meliha, Srinivasan, Seshasai, Rajabzadeh, Amin Reza, Ricci-Junior, Eduardo, Alencar, Luciana Magalhães Rebelo, Al Qahtani, Mohammed, Santos-Oliveira, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038981/
https://www.ncbi.nlm.nih.gov/pubmed/35467307
http://dx.doi.org/10.1186/s41181-022-00161-4
Descripción
Sumario:BACKGROUND: Recent advances in nanotechnology have offered new hope for cancer detection, prevention, and treatment. Nanomedicine, a term for the application of nanotechnology in medical and health fields, uses nanoparticles for several applications such as imaging, diagnostic, targeted cancer therapy, drug and gene delivery, tissue engineering, and theranostics. RESULTS: Here, we overview the current state-of-the-art of radiolabeled nanoparticles for molecular imaging and radionuclide therapy. Nanostructured radiopharmaceuticals of technetium-99m, copper-64, lutetium-177, and radium-223 are discussed within the scope of this review article. CONCLUSION: Nanoradiopharmaceuticals may lead to better development of theranostics inspired by ingenious delivery and imaging systems. Cancer nano-theranostics have the potential to lead the way to more specific and individualized cancer treatment. GRAPHICAL ABSTRACT: [Image: see text]

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