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Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients

During the recent second wave of corona virus disease 2019 (COVID-19) pandemic in India, we managed a series of gastrointestinal complications in patients with COVID-19. We aim to highlight the key presentation and clinical course and emphasize the lessons we learnt from our series of such patients....

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Autores principales: Chaugale, Sudarshan B., Singhal, Vikas, Kapoor, Deeksha, Singh, Amanjeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038998/
https://www.ncbi.nlm.nih.gov/pubmed/35471720
http://dx.doi.org/10.1007/s12664-021-01218-z
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author Chaugale, Sudarshan B.
Singhal, Vikas
Kapoor, Deeksha
Singh, Amanjeet
author_facet Chaugale, Sudarshan B.
Singhal, Vikas
Kapoor, Deeksha
Singh, Amanjeet
author_sort Chaugale, Sudarshan B.
collection PubMed
description During the recent second wave of corona virus disease 2019 (COVID-19) pandemic in India, we managed a series of gastrointestinal complications in patients with COVID-19. We aim to highlight the key presentation and clinical course and emphasize the lessons we learnt from our series of such patients. A case review of ten consecutive patients with either bowel gangrene or perforation who were managed at our centre from March 20, 2021 to June 10, 2021. Clinical-demographic details, possible etiology, radiological findings, management and outcomes have been described. Of the 10 patients, 2 presented with bowel gangrene and 8 with perforation. In our series, all these patients were diagnosed with the help of computed tomography (CT) abdomen during the 3rd week after diagnosis of COVID-19. All had received steroid medication. Both patients with bowel gangrene and 4 of 8 patients with perforation underwent surgery, while 4 were managed non-operatively. Barring one patient, all the operated patients succumbed within 5 days of surgery after rapid clinical deterioration. Non-operative management in selected patients with perforation including placement of percutaneous drains, bowel rest and antibiotics was successful. Emergency surgery for COVID-19 related intestinal gangrene or perforation was associated with high mortality in our series. Non-operative management which avoids the added stress of a major emergency surgery particularly in patients just recovering from COVID-19 may be considered in stable patients in whom perforation appears to be contained.
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spelling pubmed-90389982022-04-26 Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients Chaugale, Sudarshan B. Singhal, Vikas Kapoor, Deeksha Singh, Amanjeet Indian J Gastroenterol Case Series During the recent second wave of corona virus disease 2019 (COVID-19) pandemic in India, we managed a series of gastrointestinal complications in patients with COVID-19. We aim to highlight the key presentation and clinical course and emphasize the lessons we learnt from our series of such patients. A case review of ten consecutive patients with either bowel gangrene or perforation who were managed at our centre from March 20, 2021 to June 10, 2021. Clinical-demographic details, possible etiology, radiological findings, management and outcomes have been described. Of the 10 patients, 2 presented with bowel gangrene and 8 with perforation. In our series, all these patients were diagnosed with the help of computed tomography (CT) abdomen during the 3rd week after diagnosis of COVID-19. All had received steroid medication. Both patients with bowel gangrene and 4 of 8 patients with perforation underwent surgery, while 4 were managed non-operatively. Barring one patient, all the operated patients succumbed within 5 days of surgery after rapid clinical deterioration. Non-operative management in selected patients with perforation including placement of percutaneous drains, bowel rest and antibiotics was successful. Emergency surgery for COVID-19 related intestinal gangrene or perforation was associated with high mortality in our series. Non-operative management which avoids the added stress of a major emergency surgery particularly in patients just recovering from COVID-19 may be considered in stable patients in whom perforation appears to be contained. Springer India 2022-04-26 2022 /pmc/articles/PMC9038998/ /pubmed/35471720 http://dx.doi.org/10.1007/s12664-021-01218-z Text en © Indian Society of Gastroenterology 2022 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Case Series
Chaugale, Sudarshan B.
Singhal, Vikas
Kapoor, Deeksha
Singh, Amanjeet
Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients
title Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients
title_full Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients
title_fullStr Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients
title_full_unstemmed Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients
title_short Gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — A series of ten patients
title_sort gastrointestinal complications (gangrene or perforation) after corona virus disease 2019 — a series of ten patients
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038998/
https://www.ncbi.nlm.nih.gov/pubmed/35471720
http://dx.doi.org/10.1007/s12664-021-01218-z
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