SHANK1 facilitates non-small cell lung cancer processes through modulating the ubiquitination of Klotho by interacting with MDM2

SH3 and multiple ankyrin repeat domains 1 (SHANK1) is a scaffold protein, plays an important role in the normal function of neuron system. It has recently been shown to be a potential oncogene. In the present study, we report that the expression of SHANK1 is upregulated in non-small cell lung cancer...

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Detalles Bibliográficos
Autores principales: Chen, Bo, Zhao, Hongye, Li, Min, She, Quan, Liu, Wen, Zhang, Jiayi, Zhao, Weihong, Huang, Shuhong, Wu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039064/
https://www.ncbi.nlm.nih.gov/pubmed/35468874
http://dx.doi.org/10.1038/s41419-022-04860-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039064/
https://www.ncbi.nlm.nih.gov/pubmed/35468874
http://dx.doi.org/10.1038/s41419-022-04860-3

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