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SHANK1 facilitates non-small cell lung cancer processes through modulating the ubiquitination of Klotho by interacting with MDM2
SH3 and multiple ankyrin repeat domains 1 (SHANK1) is a scaffold protein, plays an important role in the normal function of neuron system. It has recently been shown to be a potential oncogene. In the present study, we report that the expression of SHANK1 is upregulated in non-small cell lung cancer...
Autores principales: | Chen, Bo, Zhao, Hongye, Li, Min, She, Quan, Liu, Wen, Zhang, Jiayi, Zhao, Weihong, Huang, Shuhong, Wu, Jianqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039064/ https://www.ncbi.nlm.nih.gov/pubmed/35468874 http://dx.doi.org/10.1038/s41419-022-04860-3 |
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