Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2

The global spread of SARS-CoV-2 led to major economic and health challenges worldwide. Revealing host genes essential for infection by multiple variants of SARS-CoV-2 can provide insights into the virus pathogenesis, and facilitate the development of novel therapeutics. Here, employing a genome-scal...

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Detalles Bibliográficos
Autores principales: Israeli, Ma’ayan, Finkel, Yaara, Yahalom-Ronen, Yfat, Paran, Nir, Chitlaru, Theodor, Israeli, Ofir, Cohen-Gihon, Inbar, Aftalion, Moshe, Falach, Reut, Rotem, Shahar, Elia, Uri, Nemet, Ital, Kliker, Limor, Mandelboim, Michal, Beth-Din, Adi, Israely, Tomer, Cohen, Ofer, Stern-Ginossar, Noam, Bercovich-Kinori, Adi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039069/
https://www.ncbi.nlm.nih.gov/pubmed/35469023
http://dx.doi.org/10.1038/s41467-022-29896-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039069/
https://www.ncbi.nlm.nih.gov/pubmed/35469023
http://dx.doi.org/10.1038/s41467-022-29896-z

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