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Splenic Dendritic Cells and Macrophages Drive B Cells to Adopt a Plasmablast Cell Fate

Upon encountering cognate antigen, B cells can differentiate into short-lived plasmablasts, early memory B cells or germinal center B cells. The factors that determine this fate decision are unclear. Past studies have addressed the role of B cell receptor affinity in this process, but the interplay...

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Detalles Bibliográficos
Autores principales: McNamara, Hayley A., Lahoud, Mireille H., Cai, Yeping, Durrant-Whyte, Jessica, O’Connor, James H., Caminschi, Irina, Cockburn, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039241/
https://www.ncbi.nlm.nih.gov/pubmed/35493521
http://dx.doi.org/10.3389/fimmu.2022.825207