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Atypical Rearrangements in APL-Like Acute Myeloid Leukemias: Molecular Characterization and Prognosis

Acute promyelocytic leukemia (APL) accounts for 10–15% of newly diagnosed acute myeloid leukemias (AML) and is typically caused by the fusion of promyelocytic leukemia with retinoic acid receptor α (RARA) gene. The prognosis is excellent, thanks to the all-trans retinoic acid (ATRA) and arsenic trio...

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Detalles Bibliográficos
Autores principales: Guarnera, Luca, Ottone, Tiziana, Fabiani, Emiliano, Divona, Mariadomenica, Savi, Arianna, Travaglini, Serena, Falconi, Giulia, Panetta, Paola, Rapanotti, Maria Cristina, Voso, Maria Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039303/
https://www.ncbi.nlm.nih.gov/pubmed/35494081
http://dx.doi.org/10.3389/fonc.2022.871590