Cargando…

Menadione: a platform and a target to valuable compounds synthesis

Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoqu...

Descripción completa

Detalles Bibliográficos
Autores principales: de Souza, Acácio S, Ribeiro, Ruan Carlos B, Costa, Dora C S, Pauli, Fernanda P, Pinho, David R, de Moraes, Matheus G, da Silva, Fernando de C, Forezi, Luana da S M, Ferreira, Vitor F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039524/
https://www.ncbi.nlm.nih.gov/pubmed/35529893
http://dx.doi.org/10.3762/bjoc.18.43
_version_ 1784694147519610880
author de Souza, Acácio S
Ribeiro, Ruan Carlos B
Costa, Dora C S
Pauli, Fernanda P
Pinho, David R
de Moraes, Matheus G
da Silva, Fernando de C
Forezi, Luana da S M
Ferreira, Vitor F
author_facet de Souza, Acácio S
Ribeiro, Ruan Carlos B
Costa, Dora C S
Pauli, Fernanda P
Pinho, David R
de Moraes, Matheus G
da Silva, Fernando de C
Forezi, Luana da S M
Ferreira, Vitor F
author_sort de Souza, Acácio S
collection PubMed
description Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoquinone belonging to the vitamin K group. This compound can be synthesized by different methods and it has a broad range of biological and synthetic applications, which will be highlighted in this review.
format Online
Article
Text
id pubmed-9039524
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-90395242022-05-05 Menadione: a platform and a target to valuable compounds synthesis de Souza, Acácio S Ribeiro, Ruan Carlos B Costa, Dora C S Pauli, Fernanda P Pinho, David R de Moraes, Matheus G da Silva, Fernando de C Forezi, Luana da S M Ferreira, Vitor F Beilstein J Org Chem Review Naphthoquinones are important natural or synthetic compounds belonging to the general class of quinones. Many compounds in this class have become drugs that are on the pharmaceutical market for the treatment of various diseases. A special naphthoquinone derivative is menadione, a synthetic naphthoquinone belonging to the vitamin K group. This compound can be synthesized by different methods and it has a broad range of biological and synthetic applications, which will be highlighted in this review. Beilstein-Institut 2022-04-11 /pmc/articles/PMC9039524/ /pubmed/35529893 http://dx.doi.org/10.3762/bjoc.18.43 Text en Copyright © 2022, de Souza et al. https://creativecommons.org/licenses/by/4.0/This is an open access article licensed under the terms of the Beilstein-Institut Open Access License Agreement (https://www.beilstein-journals.org/bjoc/terms/terms), which is identical to the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ). The reuse of material under this license requires that the author(s), source and license are credited. Third-party material in this article could be subject to other licenses (typically indicated in the credit line), and in this case, users are required to obtain permission from the license holder to reuse the material.
spellingShingle Review
de Souza, Acácio S
Ribeiro, Ruan Carlos B
Costa, Dora C S
Pauli, Fernanda P
Pinho, David R
de Moraes, Matheus G
da Silva, Fernando de C
Forezi, Luana da S M
Ferreira, Vitor F
Menadione: a platform and a target to valuable compounds synthesis
title Menadione: a platform and a target to valuable compounds synthesis
title_full Menadione: a platform and a target to valuable compounds synthesis
title_fullStr Menadione: a platform and a target to valuable compounds synthesis
title_full_unstemmed Menadione: a platform and a target to valuable compounds synthesis
title_short Menadione: a platform and a target to valuable compounds synthesis
title_sort menadione: a platform and a target to valuable compounds synthesis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039524/
https://www.ncbi.nlm.nih.gov/pubmed/35529893
http://dx.doi.org/10.3762/bjoc.18.43
work_keys_str_mv AT desouzaacacios menadioneaplatformandatargettovaluablecompoundssynthesis
AT ribeiroruancarlosb menadioneaplatformandatargettovaluablecompoundssynthesis
AT costadoracs menadioneaplatformandatargettovaluablecompoundssynthesis
AT paulifernandap menadioneaplatformandatargettovaluablecompoundssynthesis
AT pinhodavidr menadioneaplatformandatargettovaluablecompoundssynthesis
AT demoraesmatheusg menadioneaplatformandatargettovaluablecompoundssynthesis
AT dasilvafernandodec menadioneaplatformandatargettovaluablecompoundssynthesis
AT foreziluanadasm menadioneaplatformandatargettovaluablecompoundssynthesis
AT ferreiravitorf menadioneaplatformandatargettovaluablecompoundssynthesis