SARS-CoV-2 Spike Protein Expression In Vitro and Hematologic Effects in Mice Vaccinated With AZD1222 (ChAdOx1 nCoV-19)

Severe COVID-19 can be associated with a prothrombotic state, increasing risk of morbidity and mortality. The SARS-CoV-2 spike glycoprotein is purported to directly promote platelet activation via the S1 subunit and is cleaved from host cells during infection. High plasma concentrations of S1 subuni...

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Detalles Bibliográficos
Autores principales: Stebbings, Richard, Jones, Christopher, Cotton, Peter, Armour, Gillian, Maguire, Shaun, Skellett, Vicky, Tang, Chi-Man, Goodman, Joanne, Brady, Tyler, Takahashi, Virginia, Daunt, Andrew, Lapointe, Jean-Martin, Cohen, Taylor S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039667/
https://www.ncbi.nlm.nih.gov/pubmed/35493482
http://dx.doi.org/10.3389/fimmu.2022.836492

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