Leucine-rich repeat kinase-2 deficiency protected against cardiac remodelling in mice via regulating autophagy formation and degradation

INTRODUCTION: Leucine-rich repetitive kinase-2 (LRRK2) is a Parkinson's disease-related gene that also participates in many inflammatory diseases. However, the functional role of LRRK2 in cardiovascular disease is not clear. OBJECTIVE: In this study, we aimed to elucidate the role of LRRK2 in c...

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Detalles Bibliográficos
Autores principales: Liu, Yuan, Hao, Congqing, Zhang, Wei, Liu, Yuzhou, Guo, Sen, Li, Ran, Peng, Meng, Xu, Yawei, Pei, Xiaoxin, Yang, Haibo, Zhao, Yintao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Basic and Biological Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039674/
https://www.ncbi.nlm.nih.gov/pubmed/35499056
http://dx.doi.org/10.1016/j.jare.2021.07.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039674/
https://www.ncbi.nlm.nih.gov/pubmed/35499056
http://dx.doi.org/10.1016/j.jare.2021.07.004

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