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Overproduction of hydrogen sulfide, generated by cystathionine β-synthase, disrupts brain wave patterns and contributes to neurobehavioral dysfunction in a rat model of down syndrome

Using a novel rat model of Down syndrome (DS), the functional role of the cystathionine-β-synthase (CBS)/hydrogen sulfide (H(2)S) pathway was investigated on the pathogenesis of brain wave pattern alterations and neurobehavioral dysfunction. Increased expression of CBS and subsequent overproduction...

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Detalles Bibliográficos
Autores principales:	Panagaki, Theodora, Lozano-Montes, Laura, Janickova, Lucia, Zuhra, Karim, Szabo, Marcell P., Majtan, Tomas, Rainer, Gregor, Maréchal, Damien, Herault, Yann, Szabo, Csaba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Articles from the Special Issue on Recent advances in sulfur biology and chemistry, Edited by: Dr. Peter Nagy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039679/ https://www.ncbi.nlm.nih.gov/pubmed/35042677 http://dx.doi.org/10.1016/j.redox.2022.102233

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