Rare coding variants in DNA damage repair genes associated with timing of natural menopause

The age of menopause is associated with fertility and disease risk, and its genetic control is of great interest. We use whole-exome sequences from 132,370 women in the UK Biobank to test for associations between rare damaging variants and age at natural menopause. Rare damaging variants in five gen...

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Detalles Bibliográficos
Autores principales: Ward, Lucas D., Parker, Margaret M., Deaton, Aimee M., Tu, Ho-Chou, Flynn-Carroll, Alexander O., Hinkle, Gregory, Nioi, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039695/
https://www.ncbi.nlm.nih.gov/pubmed/35493704
http://dx.doi.org/10.1016/j.xhgg.2021.100079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039695/
https://www.ncbi.nlm.nih.gov/pubmed/35493704
http://dx.doi.org/10.1016/j.xhgg.2021.100079

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