Cargando…
Linear Mixed-Effect Models Through the Lens of Hardy–Weinberg Disequilibrium
For genetic association studies with related individuals, the linear mixed-effect model is the most commonly used method. In this report, we show that contrary to the popular belief, this standard method can be sensitive to departure from Hardy–Weinberg equilibrium (i.e., Hardy–Weinberg disequilibri...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039721/ https://www.ncbi.nlm.nih.gov/pubmed/35495131 http://dx.doi.org/10.3389/fgene.2022.856872 |