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Leveraging interacting signaling pathways to robustly improve the quality and yield of human pluripotent stem cell-derived hepatoblasts and hepatocytes

Pluripotent stem cell (PSC)-derived hepatocyte-like cells (HLCs) have shown great potential as an alternative to primary human hepatocytes (PHHs) for in vitro modeling. Several differentiation protocols have been described to direct PSCs toward the hepatic fate. Here, by leveraging recent knowledge...

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Detalles Bibliográficos
Autores principales:	Raggi, Claudia, M’Callum, Marie-Agnès, Pham, Quang Toan, Gaub, Perrine, Selleri, Silvia, Baratang, Nissan Vida, Mangahas, Chenicka Lyn, Cagnone, Gaël, Reversade, Bruno, Joyal, Jean-Sébastien, Paganelli, Massimiliano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039749/ https://www.ncbi.nlm.nih.gov/pubmed/35120625 http://dx.doi.org/10.1016/j.stemcr.2022.01.003

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