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Developmental thyroid disruption permanently affects the neuroglial output in the murine subventricular zone

Neural stem cells (NSCs) in the adult brain are a source of neural cells for brain injury repair. We investigated whether their capacity to generate new neurons and glia is determined by thyroid hormone (TH) during development because serum levels peak during postnatal reorganization of the main NSC...

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Detalles Bibliográficos
Autores principales: Vancamp, Pieter, Le Blay, Karine, Butruille, Lucile, Sébillot, Anthony, Boelen, Anita, Demeneix, Barbara A., Remaud, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039754/
https://www.ncbi.nlm.nih.gov/pubmed/35120623
http://dx.doi.org/10.1016/j.stemcr.2022.01.002