Deriving waveform parameters from calcium transients in human iPSC-derived cardiomyocytes to predict cardiac activity with machine learning

Human induced pluripotent stem cell-derived cardiomyocytes have been established to detect dynamic calcium transients by fast kinetic fluorescence assays that provide insights into specific aspects of clinical cardiac activity. However, the precise derivation and use of waveform parameters to predic...

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Detalles Bibliográficos
Autores principales: Yang, Hongbin, Stebbeds, Will, Francis, Jo, Pointon, Amy, Obrezanova, Olga, Beattie, Kylie A., Clements, Peter, Harvey, James S., Smith, Graham F., Bender, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039838/
https://www.ncbi.nlm.nih.gov/pubmed/35148844
http://dx.doi.org/10.1016/j.stemcr.2022.01.009

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