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P05 In vivo efficacy of VRP-034 in lung and thigh infection models

BACKGROUND: Polymyxin B-induced kidney injury is an important clinical concern that undermines patient care. This injury occurs in 30%–60% of patients receiving systemic polymyxin B (PMB). VRP-034, a novel PMB formulation, has previously shown a promising safety profile as compared with marketed PMB...

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Detalles Bibliográficos
Autores principales: Vishwakarma, Kamlesh Kumar, Payasi, Anurag, Kumar, Shailesh, Sharma, Arun, Chaudhary, Saransh, Aggarwal, Anmol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040012/
http://dx.doi.org/10.1093/jacamr/dlac004.004