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Cytolytic CD4(+) and CD8(+) Regulatory T-Cells and Implications for Developing Immunotherapies to Combat Graft-Versus-Host Disease

Regulatory T-cells (Treg) are critical for the maintenance of immune homeostasis and tolerance induction. While the immunosuppressive mechanisms of Treg have been extensively investigated for decades, the mechanisms responsible for Treg cytotoxicity and their therapeutic potential in regulating immu...

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Detalles Bibliográficos
Autores principales:	Bolivar-Wagers, Sara, Larson, Jemma H., Jin, Sujeong, Blazar, Bruce R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040077/ https://www.ncbi.nlm.nih.gov/pubmed/35493508 http://dx.doi.org/10.3389/fimmu.2022.864748

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