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Shared inflammatory and skin-specific gene signatures reveal common drivers of discoid lupus erythematosus in canines, humans and mice

Autoimmune skin diseases are complex and are thought to arise from a combination of genetics and environmental exposures, which trigger an ongoing immune response against self-antigens. Companion animals including cats and dogs are known to develop inflammatory skin conditions similar to humans and...

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Detalles Bibliográficos
Autores principales: Garelli, Colton J., Wong, Neil B., Piedra-Mora, Cesar, Wrijil, Linda M., Scarglia, Gina, David, Clement N., Almela, Ramón M., Robinson, Nicholas A., Richmond, Jillian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040131/
https://www.ncbi.nlm.nih.gov/pubmed/35492392
http://dx.doi.org/10.1016/j.crimmu.2021.03.003

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