FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?

FGF21 is a liver-derived hormone primarily involved in glucose/lipid metabolism. A recent study by Flippo and colleagues(1) demonstrates that administration of FGF21 or an FGF21 analog suppresses alcohol consumption in rodents and non-human primates, likely through an amygdalo-striatal circuit.

Detalles Bibliográficos
Autores principales: Wang, Tammy, Farokhnia, Mehdi, Leggio, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040172/
https://www.ncbi.nlm.nih.gov/pubmed/35492877
http://dx.doi.org/10.1016/j.xcrm.2022.100578
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author Wang, Tammy
Farokhnia, Mehdi
Leggio, Lorenzo
author_facet Wang, Tammy
Farokhnia, Mehdi
Leggio, Lorenzo
author_sort Wang, Tammy
collection PubMed
description FGF21 is a liver-derived hormone primarily involved in glucose/lipid metabolism. A recent study by Flippo and colleagues(1) demonstrates that administration of FGF21 or an FGF21 analog suppresses alcohol consumption in rodents and non-human primates, likely through an amygdalo-striatal circuit.
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spelling pubmed-90401722022-04-27 FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment? Wang, Tammy Farokhnia, Mehdi Leggio, Lorenzo Cell Rep Med Spotlight FGF21 is a liver-derived hormone primarily involved in glucose/lipid metabolism. A recent study by Flippo and colleagues(1) demonstrates that administration of FGF21 or an FGF21 analog suppresses alcohol consumption in rodents and non-human primates, likely through an amygdalo-striatal circuit. Elsevier 2022-03-15 /pmc/articles/PMC9040172/ /pubmed/35492877 http://dx.doi.org/10.1016/j.xcrm.2022.100578 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Spotlight
Wang, Tammy
Farokhnia, Mehdi
Leggio, Lorenzo
FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
title FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
title_full FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
title_fullStr FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
title_full_unstemmed FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
title_short FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
title_sort fgf21 regulates alcohol intake: new hopes on the rise for alcohol use disorder treatment?
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040172/
https://www.ncbi.nlm.nih.gov/pubmed/35492877
http://dx.doi.org/10.1016/j.xcrm.2022.100578
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