FOXG1 dose tunes cell proliferation dynamics in human forebrain progenitor cells

Heterozygous loss-of-function mutations in Forkhead box G1 (FOXG1), a uniquely brain-expressed gene, cause microcephaly, seizures, and severe intellectual disability, whereas increased FOXG1 expression is frequently observed in glioblastoma. To investigate the role of FOXG1 in forebrain cell prolife...

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Detalles Bibliográficos
Autores principales: Hettige, Nuwan C., Peng, Huashan, Wu, Hanrong, Zhang, Xin, Yerko, Volodymyr, Zhang, Ying, Jefri, Malvin, Soubannier, Vincent, Maussion, Gilles, Alsuwaidi, Shaima, Ni, Anjie, Rocha, Cecilia, Krishnan, Jeyashree, McCarty, Vincent, Antonyan, Lilit, Schuppert, Andreas, Turecki, Gustavo, Fon, Edward A., Durcan, Thomas M., Ernst, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040178/
https://www.ncbi.nlm.nih.gov/pubmed/35148845
http://dx.doi.org/10.1016/j.stemcr.2022.01.010

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