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A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes

Mucormycosis is a rare, potentially life-threatening disease that is growing during the Covid-19 pandemic. This study reports a case of an 11-year-old patient with fatal Covid-19-related pulmonary mucormicosis and diabetes mellitus with ketoacidosis. The diagnosis was set post mortem. It was based o...

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Autores principales: Pekova, L., Gulubova, M., Hadzhi, M., Mitev, M., Angelova, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040516/
https://www.ncbi.nlm.nih.gov/pubmed/35494551
http://dx.doi.org/10.1016/j.rmcr.2022.101655
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author Pekova, L.
Gulubova, M.
Hadzhi, M.
Mitev, M.
Angelova, S.
author_facet Pekova, L.
Gulubova, M.
Hadzhi, M.
Mitev, M.
Angelova, S.
author_sort Pekova, L.
collection PubMed
description Mucormycosis is a rare, potentially life-threatening disease that is growing during the Covid-19 pandemic. This study reports a case of an 11-year-old patient with fatal Covid-19-related pulmonary mucormicosis and diabetes mellitus with ketoacidosis. The diagnosis was set post mortem. It was based on histochemical detection of the causative agent. Massive hemoptysis due to erosion of a large pulmonary vessel caused mechanical asphyxia and lethal outcome. Pulmonary mucormycosis may be highly suspected in patients with long-term Covid-19, poorly controlled diabetes mellitus with ketoacidosis, and corticosteroid therapy. Early diagnosis and treatment with Amphotericin B are potentially curative options for this invasive fungal infection and can led to better outcome.
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spelling pubmed-90405162022-04-26 A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes Pekova, L. Gulubova, M. Hadzhi, M. Mitev, M. Angelova, S. Respir Med Case Rep Case Report Mucormycosis is a rare, potentially life-threatening disease that is growing during the Covid-19 pandemic. This study reports a case of an 11-year-old patient with fatal Covid-19-related pulmonary mucormicosis and diabetes mellitus with ketoacidosis. The diagnosis was set post mortem. It was based on histochemical detection of the causative agent. Massive hemoptysis due to erosion of a large pulmonary vessel caused mechanical asphyxia and lethal outcome. Pulmonary mucormycosis may be highly suspected in patients with long-term Covid-19, poorly controlled diabetes mellitus with ketoacidosis, and corticosteroid therapy. Early diagnosis and treatment with Amphotericin B are potentially curative options for this invasive fungal infection and can led to better outcome. Elsevier 2022-04-26 /pmc/articles/PMC9040516/ /pubmed/35494551 http://dx.doi.org/10.1016/j.rmcr.2022.101655 Text en © 2022 Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Pekova, L.
Gulubova, M.
Hadzhi, M.
Mitev, M.
Angelova, S.
A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_full A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_fullStr A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_full_unstemmed A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_short A case of Covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
title_sort case of covid-19-associated invasive pulmonary mucormycosis in a pediatric patient with a newly diagnosed diabetes
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040516/
https://www.ncbi.nlm.nih.gov/pubmed/35494551
http://dx.doi.org/10.1016/j.rmcr.2022.101655
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