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Aptamer-functionalized pH-sensitive liposomes for a selective delivery of echinomycin into cancer cells

Echinomycin (quinomycin A) is a peptide antibiotic from the quinoxaline family, which has a DNA bifunctional intercalating activity and an inhibitor of hypoxia-inducible factor (HIF1α). Echinomycin was discovered in 1957 as a potent antitumor agent; however, it was not successful in clinical use due...

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Detalles Bibliográficos
Autores principales:	Lafi, Zainab, Alshaer, Walhan, Hatmal, Ma'mon M., Zihlif, Malek, Alqudah, Dana A., Nsairat, Hamdi, Azzam, Hanan, Aburjai, Talal, Bustanji, Yasser, Awidi, Abdalla
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040599/ https://www.ncbi.nlm.nih.gov/pubmed/35479561 http://dx.doi.org/10.1039/d1ra05138e

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