N-Aryl iminochromenes inhibit cyclooxygenase enzymes via π–π stacking interactions and present a novel class of anti-inflammatory drugs

Cyclooxygenase enzymes (COX1/2) have been widely studied and noted for their role in the biosynthesis of inflammation-induced proteins, prostaglandins and thromboxane. Multiple anti-inflammatory drugs have been developed to target these two enzymes, but most of them appeared to have notable adverse...

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Detalles Bibliográficos
Autores principales: Nguyen, Ha Thi, Vu, Thien-Y., Vijay Kumar, A., Hoang, Vo Nguyen Huy, My, Pham Thi Ngoc, Mandal, Prashant S., Tatipamula, Vinay Bharadwaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040635/
https://www.ncbi.nlm.nih.gov/pubmed/35479538
http://dx.doi.org/10.1039/d1ra04407a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040635/
https://www.ncbi.nlm.nih.gov/pubmed/35479538
http://dx.doi.org/10.1039/d1ra04407a

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