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N-Aryl iminochromenes inhibit cyclooxygenase enzymes via π–π stacking interactions and present a novel class of anti-inflammatory drugs

Cyclooxygenase enzymes (COX1/2) have been widely studied and noted for their role in the biosynthesis of inflammation-induced proteins, prostaglandins and thromboxane. Multiple anti-inflammatory drugs have been developed to target these two enzymes, but most of them appeared to have notable adverse...

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Detalles Bibliográficos
Autores principales:	Nguyen, Ha Thi, Vu, Thien-Y., Vijay Kumar, A., Hoang, Vo Nguyen Huy, My, Pham Thi Ngoc, Mandal, Prashant S., Tatipamula, Vinay Bharadwaj
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040635/ https://www.ncbi.nlm.nih.gov/pubmed/35479538 http://dx.doi.org/10.1039/d1ra04407a

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