Sequence-specific capture and concentration of viral RNA by type III CRISPR system enhances diagnostic

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Type-III CRISPR-Cas systems have recently been adopted for sequence-specific detection of SARS-CoV-2. Here, we make two major advances that simultaneously limit sample handling and significantly enhance the sensitivity of SARS-CoV-2 RNA detection directly from patient samples. First, we repurpose th...

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Detalles Bibliográficos
Autores principales: Nemudraia, Anna, Nemudryi, Artem, Buyukyoruk, Murat, Scherffius, Andrew M., Zahl, Trevor, Wiegand, Tanner, Pandey, Shishir, Nichols, Joseph E., Hall, Laina, McVey, Aidan, Lee, Helen H, Wilkinson, Royce A., Snyder, Laura R., Jones, Joshua D., Koutmou, Kristin S., Santiago-Frangos, Andrew, Wiedenheft, Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9040678/
https://www.ncbi.nlm.nih.gov/pubmed/35475170
http://dx.doi.org/10.21203/rs.3.rs-1466718/v1
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